Skip to main content Skip to footer

Troubleshooting GC-MS

Course Details Premier

This learning path on troubleshooting GC-MS covers sensitivity issues, interpreting tune reports for ion optics, mass accuracy, and detector performance. It includes identifying contamination, leaks, and column degradation. Practical strategies focus on pump maintenance, vacuum integrity, and optimizing ionization for consistent, high-sensitivity GC-MS analysis.

5 Quick Guides

Troubleshooting GC-MS

5 Items

GC-MS Troubleshooting - Sensitivity
Quick Guide

GC-MS Troubleshooting - Sensitivity

Many diverse problems can cause a reduction in sensitivity with GC-MS. In this quick guide, we explore some of the most common causes, including sub-optimal tuning, detector problems, contamination, and sample introduction.

What Can a GC-MS Tune Report Tell You?
Quick Guide

What Can a GC-MS Tune Report Tell You?

A GC-MS tune report is invaluable as it provides information on how well the instrument is working, indicates if cleaning or maintenance is required, serves as a chronicle of how the instrument has performed in the past, and can be used to diagnose problems when troubleshooting. 

GC-MS Contamination
Quick Guide

GC-MS Contamination

Contamination is usually identified by excessive background ions in the mass spectrum. Contamination can originate from GC or MS components in the system. The source of the contamination can sometimes be determined by identifying the contaminant. Some contaminants are much more likely to originate in the GC, some others in the MS.

GC-MS Leak Detection
Quick Guide

GC-MS Leak Detection

If it is expected that there is a leak in a GC-MS system there are a few things that can be done to try and identify the source of the leak in order to repair it, which is the focus of this quick guide.

Vacuum Pump Maintenance
Quick Guide

Vacuum Pump Maintenance

This quick guide discusses the maintenance of  rotary, foreline, diffusion, and turbomolecular pumps.