Optimizing GC Carrier Gases
This learning path on optimizing GC carrier gases covers selecting helium, hydrogen, or nitrogen based on efficiency, resolution, and detector compatibility. It includes adjusting flow rates, controlling inlet pressure, and ensuring gas purity. Practical strategies focus on safety, cost-effectiveness, and method adaptation for optimal chromatographic performance and sensitivity.
1 Module 3 Webcasts 1 Quick Guide
5 Items
Gas Supply and Pressure Control
The aims of this module include outlining the nature and quality of the gases required for GC analysis, as well as highlighting the various methods for controlling gas pressure and cleanliness including troubleshooting strategies. The use of gas generators as a viable alternative to cylinders for GC gas supply will be discussed. The principles of manual and electronic pressure control for GC carrier, inlet, and detector gas regulation are described as well as the differences between constant pressure and constant flow experiments.
Gas Quality for GC
This webcast will discuss all of the important considerations on selecting the correct gas with the correct cleanliness for your GC system and detector. Common problems will also be highlighted in order for GC users to spot them quickly when they occur.
Translating GC Methods from Helium to Hydrogen Carrier Gas
This webcast will provide practical information on how to change methods quickly and simply to hydrogen carrier gas. The chromatographic benefits of adopting modern column geometries in conjunction with hydrogen carrier gas will be discussed. We will discuss regulatory challenges, such as, the need for method re-validation and approaches to verifying translated methods.
Is Hydrogen the Best Carrier Gas for GC?
Is hydrogen the best carrier gas? And if so what benefits can we gain from using it?
Nitrogen as a Carrier Gas for Capillary Gas Chromatography
This educational event will explain how to identify methods which may be compatible with nitrogen carrier, and shows how method translation can be used to establish acceptable chromatographic performance. We will also discuss the use of narrower internal diameter capillary GC columns to give comparable performance to existing methods and for high efficiency when developing new methods with nitrogen carrier.