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First Steps in SPE

Course Details Premier

This learning path on first steps in SPE covers selecting the right sorbent, understanding retention mechanisms, and following the key steps: conditioning, sample loading, washing, and elution. It includes choosing appropriate solvents and optimizing recoveries. 

2 Modules 1 Webcast 3 Quick Guides

First Steps in SPE

6 Items

Molecular Properties
Module

Molecular Properties

This module introduces the concept of functional group chemistry as a means of targeting separation mechanisms in liquid and solid phase extraction (SPE).

SPE - What Can You Learn in 5 Minutes?
Quick Guide

SPE - What Can You Learn in 5 Minutes?

This quick guide focusses on the three main parameters to optimize in SPE, which are the choice of column sorbent, the choice of wash solvent, and the choice of eluting solvent.

SPE Overview
Module

SPE Overview

This module introduces the terminology associated with solid phase extraction (SPE). It explains the chemistry and physical properties associated with SPE sorbents and substrates, the different steps in a solid phase extraction protocol, sorbent selection, eluent solvent strength optimization, and the use of pH and ionic additives to control selectivity in SPE.

Analyte Chemistry for SPE
Quick Guide

Analyte Chemistry for SPE

This quick guide discusses the first step in developing a solid phase extraction (SPE) method; understanding your analyte(s) chemistry.

Understanding the Mechanisms of Solid Phase Extraction
Webcast

Understanding the Mechanisms of Solid Phase Extraction

This webcast is aimed to help you to understand all of the key stages in SPE protocol development. This understanding is crucial for improving your SPE technique and ultimately to developing better solid phase extraction methods. 

SPE Mechanism Selection
Quick Guide

SPE Mechanism Selection

This quick guide will detail how to select the correct SPE extraction mechanism for your analyte(s).