Conductivity Detection for Cation Chromatography - Advantages and Disadvantages of Suppression

Conductivity detection is separated into two applications: suppressed and non-suppressed. There is universal agreement in the analytical community that suppressor systems are necessary for sensitive and specific anion exchange chromatography. For cation exchange chromatography, there is still an ongoing discussion about if a suppressor system is required. 

Topics include:

• Classification of detection methods
• When to consider non-suppressed conductivity detection
• The use of suppressed conductivity detection for utilizing high-capacity cation exchange columns or performing gradient elution techniques