CHROMtalks - Troubleshooting GC Sample Introduction

GC instrumentation is mechanically relatively simple and robust. However, there are a few key areas where problems regularly arise. One of the most important parts of a GC method is getting your sample onto the column for analysis. If you get this wrong, the data will be incorrect and you’ll be left with a difficult problem to troubleshoot. This presentation will therefore focus on the process of GC sample introduction and where it can go wrong - from issues with the autosampler components, to contamination, then on to the inlet. Topics addressed will include needles, plungers, contamination, septa (bleed and leaks), liners (contamination, adsorption), and split/splitless inlets.