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Although Soxhlet extraction was developed in 1876, it is still widely used in many industry areas to extract analytes from solid matrices. It is, in fact, still seen as the gold standard technique for extraction from solid matrices against which others are compared. This quick guide details how Soxhlet extraction works, parameters that require optimization, and how improvements to the methodology and automation have allowed an increase in throughput and improved reproducibility. 

Soxhlet Extraction