Electrospray Ionization (ESI) Technique

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Electrospray Ionization (ESI) Technique

Electrospray is a method by which ions present in a solution can be transferred to the gas phase. The process involves the application of an electric field across an interface which acts to form an electrochemical cell in the interface. This module discusses important parameters when carrying out electrospray ionization (ESI). Find out practical tips for overcoming ion suppression, optimizing sprayer position, and the role pH plays in signal intensity.

Topics include:

Ion suppression principles
Ion suppression in practice
Mass dependence of the ion signal
Optimizing the sprayer position
Solute changes in evaporating droplets
pH versus ion intensity

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