Quadrupole Mass Analyzers

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Quadrupole Mass Analyzers

In quadrupole mass analyzing devices, electric fields are used to separate ions according to their mass-to-charge ratio (m/z) as they pass along the central axis of four parallel equidistant rods (or poles) that have fixed (DC) and alternating (RF) voltages applied to them. This module will explain the theory and principles of quadrupole mass analyzers.

Topics include:

Quadrupole rods
Quadrupole voltages
Quadrupole electrostatic fields
Quadrupole ion trajectories
Equations of motion
Quadrupole mass analyzers - mass gain and offset
Quadrupole resolution and sensitivity
Quadrupole data acquisition modes
Quadrupole scan vs. selected ion modes
RF only ion bridges
Quadrupole mass accuracy
Quadrupole performance limitations
Quadrupole scanning speeds

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