LC/MS MAM Analysis of Adeno-Associated Virus Particles

Adeno-associated viruses (AAVs) are an important and emerging tool enabling the delivery of next-generation gene therapies. AAV critical quality attributes (CQAs) must be maintained for the safety and efficacy of the therapeutic, but can be challenging to analyze. This webcast will discuss several workflows for characterizing AAV CQAs, including product identity, post-translational modifications, and host cell proteins. 

Topics include:

• Method optimization parameters for separating capsid proteins
• Technical challenges associated with AAV capsid analysis
• Learn about the utility of mass spectrometry for AAV characterization